The global market for treating Palmoplantar Pustulosis (PPP) was robust in 2021 and is expected to grow rapidly over the forecast period due to the rising occurrences of skin diseases and sores among adults worldwide. PPP causes blister-like sores on the palms of the hands and soles of the feet and is an auto-inflammatory illness.
While there is no definitive cure for this ailment, available treatments can help mitigate its symptoms. Primary contributors to PPP include obesity, stress, drug dependency, and infections, and these are anticipated to stimulate revenue expansion in the PPP treatment sector. Conversely, a scarcity of essential standard medications and limited awareness about PPP treatment choices are factors likely to restrain the market's revenue growth.
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The North America market is expected to account for the largest revenue share in the global market due to the strong presence of key players and the rapid adoption of sophisticated technology.
Key Players in the Palmoplantar Pustulosis Treatment Market –
- GlaxoSmithKline plc
- Aristea Therapeutics, Inc.
- AnaptysBio, Inc.
- Pfizer Inc.
- AstraZeneca plc
- Taiho Pharmaceutical Co., Ltd.
- Sanofi
- Sandoz International GmbH
- Novartis AG
- Almirall, LLC
- Abbvie Inc.
- Bristol-Myers Squibb Company
- UCB S.A.
- Mylan N.V.
- Eli Lilly and Company
- Amgen Inc.
Meanwhile, the Asia Pacific market is expected to register a significantly fast revenue CAGR over the forecast period due to rising skin disease cases and favorable reimbursement policies for biological medicines in India, China, and Brazil.
Notable Innovations in the Palmoplantar Pustulosis Treatment Market –
There have been several notable innovations in the treatment of Palmoplantar Pustulosis (PPP) in recent years. Some of them are:
- Biologic therapies: Biologic drugs, also known as biologics, are a type of treatment that target specific parts of the immune system that play a role in causing PPP. For example, drugs like Adalimumab, Infliximab, and Ustekinumab are some of the biologic drugs that have been approved for the treatment of PPP.
- Topical therapies: Several new topical therapies have been developed for the treatment of PPP. These include Calcipotriol, a synthetic form of vitamin D, and Tacrolimus, an immunosuppressive drug. These drugs have been shown to be effective in reducing inflammation and preventing the formation of pustules.
- Phototherapy: Phototherapy is a type of treatment that uses light to reduce inflammation and improve skin conditions. Narrowband UVB therapy and Psoralen plus UVA (PUVA) therapy are some of the phototherapy techniques that have been shown to be effective in treating PPP.
- Combination therapies: Combination therapies are a combination of two or more drugs that are used to treat PPP. For example, a combination of topical steroids and Calcipotriol has been shown to be effective in reducing inflammation and preventing the formation of pustules.
- Stem cell therapy: Stem cell therapy is a relatively new approach that involves the use of stem cells to regenerate damaged tissue. Studies have shown that stem cell therapy may be effective in treating PPP by promoting the regeneration of skin tissue and reducing inflammation.
Topical medications and systemic medications are being used to address symptoms, and further advancements in developing drugs for treating PPP are growing rapidly. For instance, in June 2022, Aristea Therapeutics Inc., a clinical-stage immunology company, initiated a Phase 1 clinical study of its next-generation calcitonin gene-related peptide (CGRP) antibody for the treatment of PPP.
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